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VERSION:2.0
CALSCALE:GREGORIAN
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UID:6f929d824cfd17df3dddfad4ae46103b
DTSTAMP:20260915T210258Z
SUMMARY:Ebba Jarlman - Institutionen för kliniska vetenskaper\, Lund
DESCRIPTION:Kontakt: ebba.jarlman@med.lu.se\n\nTitle: Cerebral Palsy – pa
 in and skeletal healthMain supervisor: Ann I. Alriksson-SchmidtReviewers: 
 Per Swärd\, Karin Dalhammar\, Kristina MattsonAbstractBackgroundCerebral 
 Palsy (CP) is a common motor disorder and is associated with secondary mus
 culoskeletal complications such as deformities\, pain\, reduced bone miner
 al density (BMD)\, and fragility fractures. However\, individuals with CP 
 vary substantially in their level of mobility\, and the prevalence of seco
 ndary complications differs across mobility subgroups.Research questions:&
 nbsp\;Study I: In individuals with CP:&nbsp\;How prevalent is pain in the 
 foot and lower leg?Which factors are associated with an increased risk of 
 pain in the foot and lower leg?Studies II–III: In children with CP:&nbsp
 \;How does BMD vary according to mobility level?How does BMD change over t
 ime?Which factors are associated with low BMD or poor bone accrual\, do th
 ese associations differ by level of mobility?How are low BMD and poor bone
  accrual associated with the development of secondary complications such a
 s pain\, fractures\, or skeletal deformity?Preliminary resultsPain in the 
 foot and lower leg was common in individuals with CP\, affecting 21%.Older
  age\, higher mobility level\, female sex and decreased range of motion of
  the ankle&nbsp\;were associated with increased odds of foot and lower-leg
  pain.&nbsp\;BMD differed substantially by mobility level: a BMD Z-score 
 ≤ −2 was observed in 13% of children with high mobility compared with 
 73% of children with low mobility.Low BMI was associated with low BMD rega
 rdless of level of mobility\, whereas other risk factors&nbsp\;differed be
 tween mobility subgroups.SignificanceIndividuals with CP at different leve
 ls of mobility face varying challenges and risks for secondary complicatio
 ns. By identifying mobility-specific risk factors and stratifying outcomes
  according to mobility level\, this research aims to facilitate earlier id
 entification of individuals at risk of pain\, low BMD\, and poor bone accr
 ual\, thereby supporting more individualized prevention\, monitoring\, and
  management strategies in the care of individuals with CP.Published studie
 sJarlman E\, Hägglund G\, Alriksson AI.&nbsp\;Foot and lower leg pain in 
 children and adults with cerebral palsy: a population-based register study
  on 5\,122 individuals. BMC Musculoskelet disord. 2024 May 18\;25(1):391. 
 Doi:&nbsp\;doi: 10.1186/s12891-024-07486-y. PMID: 38762469. PMCID:&nbsp\;P
 MC11102238.\n\nMer information om händelsen: https://www.intramed.lu.se/e
 venemang/ebba-jarlman-institutionen-kliniska-vetenskaper-lund
DTSTART;TZID=GMT:20260824T130000
DTEND;TZID=GMT:20260824T130000
LOCATION:Wigerthuset\, Remissgatan 4\, Lund
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